Quaternium-73, also known as Pionin, is a yellow odorless crystalline powder with good light and heat stability. It is stable in the pH range of 5.5 to 8.0 and has high safety. Purinin has antistatic, bactericidal, antibacterial, antiseptic, emulsifying and dispersing properties.It is a highly effective antibacterial and anti-inflammatory agent that can improve symptoms of acne, blackheads and polyacne.As a preservative, it can extend the shelf life of the product; the dosage is low and the cost performance is high.It is widely used in the field of cosmetics and skin care products. Pionin for skin can inhibit the formation of melanin, reduce skin inflammation, and inhibit bacteria and fight acne.Baisifu is a China Quaternium-73supplier and we have passed ISO 9001 & ISO 14001 certifications. Our products are equipped with COA, MSDS, and TDS quality reports.Our products are not tested on animals. Free samples are available for you.
Cas No.:15763-48-1
Appearance: Yellow crystalline powder
Similar Name: Pionin/Purinin
Solubility:Slightly soluble in water
| CAS Number | 2 |
| Appearance | Yellow crystalline powder |
Package:
1kg/bag; 25kg/Carton. Customized accepted.
General Information:
| Cas No.: | 15763-48-1 |
| MF: | C23H39IN2S2 |
| MW: | 534.6 |
| EINECS: | 239-852-5 |
| Appearance: | Yellow odorless crystalline powder |
| Solubility | Slightly soluble in water |
| Store | Store in cool dry place away from light, room temperature. |
| Shelf Life | 2 year |

Quaternium 73 is effective at very low concentration of 0.005-0.02% therefore, it is suitable for oily, acne-prone and combination skin facial cleansers.
It is primarily used as a powerful antibacterial agent for acne-prone skin by reducing and preventing breakouts through targeting acne-causing bacteria.
In toners, quaternium 73 works well in oily and acne-prone skin thus it is used mainly for antibacterial and anti-acne control.
It acts as a preservative booster with a light, non-sticky feel since it is gentle, non-exfoliating and suitable for daily use.
Quaternium 73 is mainly used in lotion for antibacterial and anti-acne control hence it helps prevent and reduce breakouts, mainly in body or facial lotions for acne-prone skin.
However, it is suitable for leave-on formulations when properly balanced at very low concentrations of 0.005-0.01%.
Remember, quaternium 73 does not affect lotion texture because it is non-comedogenic. Therefore, it acts as a preservative booster, supporting product microbial stability.
Here it helps to control acne-causing bacteria in lightweight, leave on products since it is a non-comedogenic and does not leave residue.
It acts as a preservative booster thus is suitable for watery, fast-absorbing essences.
Since it’s suitable for oily and acne-prone skin, quaternium 73 is mainly used for antibacterial and anti-acne protection.
Quaternium 73 does not condition hair nor improve slip or replace anti-fungal dandruff. It is used for antibacterial scalp care.
In shampoos, it is very effective at low levels thus it works well on oily and problem scalps. Moreover, it acts as a preservative booster so it helps control scalp bacteria, color, and scalp acne.
Quaternium 73 supports microbial stability as a preservative booster thus helps control bacteria on the scalp, reducing scalp acne and color.
In conditioners, it is effective at a very low concentration so it does not provide hair conditioning, detangling or shines; rather it is used for antibacterial and scalp-care purposes.
In shower gel, quaternium 73 is used for antibacterial and anti-acne skin protection therefore, it keeps the skin clean and refreshed by controlling skin bacteria.
This cosmetic ingredient remains effective even on oily skin areas since it reduces microbial overgrowth without over-drying.
Quaternium 73 acts as a preservative booster by reducing the need for high levels of traditional preservatives thus improving microbial safety of the shower gel.

Quaternium 73 is most effective in acidic formulation of pH 3.5-6.0 because it is a cationic conditioning polymer hence it binds effectively to negatively charged surfaces like hair or skin.
Remember, it may lose its effectiveness or may precipitate if the pH is more than 7 since high pH reduces its cationic activity.
The recommended concentration depends on the type of the product, so overuse may leave a slightly sticky or heavy feel on hair or skin. It can interact with anionic surfactants since it’s a cationic polymer thus the pH and the surfactant system affect effective concentration.
Quaternium 73 is soluble in water so it is best to pre-dissolve in water before adding to the formulation. More importantly, it is slightly soluble in glycerin and practically insoluble in oils or non-polar solvents therefore it should be incorporated in aqueous phases of formulations.
It is stable up to 80c in aqueous solutions thus should be added later in the formulation process to avoid degradation.
This helps maintain cationic activity and solubility.

Quaternium is designed for safe conditioning and film-forming on skin and hair since its water-soluble quaternary ammonium polymer. It is made of an acrylic-based polymer backbone with permanent positive charges and anti-static performance in cosmetic products.
Quaternium 73 works by binding to negatively charged skin and hair since it’s a positively charged conditioning polymer.
Its performances is based on electrostatic attraction and film formation since it deposits evenly on hair shafts or skin, even in rinse of products.
Because of its ionic bonding, part of the polymer remains after rinsing hence improving softness, moisture retention and manageability without clogging pores.
Quaternium 73 works on the surface hence does not treat acne or kill bacterial since it’s not an active treatment or preservative.

This ingredient has a mild, supportive antimicrobial activity due to its positive charge thus can reduce microbial attachment on skin or hair surface.
It does not inhibit melanin formation but it indirectly improves skin appearance by hydration and barrier support.
Quaternium 73 hydrates and soothes skin to minimize redness and friction therefore it indirectly reduces skin irritation and inflammation.
It supports acne-prone skin but does not treat acne directly thus it maintain skin barrier, which can prevent irritation-induced breakouts.
Quaternium indirectly improves hydration and skin barrier, making skin look smoother and radiant.
It neutralizes static electricity on hair therefore it is useful in shampoos, conditioners and hair serum for dry or fizzy hair.

Quaternium 73 is a safe, compliant conditioning ingredient that is generally well tolerated by skin and scalp.
This cosmetic ingredient is approved for cosmetic use in major markets like EU, USA and internationally hence it is not banned under EU cosmetic regulation [EC] No.1223/2009.
When it is properly formulated, it must be listed on labels under its INCI name [Quaternium-73/Polyquaternium-73].

Baisifu is an ISO 22716 manufacturer and supplier of cosmetic-grade quaternium 73 supplier in China. With every quaternium 73 you get the certificate of analysis (CoA), product data sheet and free samples.
Upon request, Baisifu can also help you in product formulation to help you develop new products. So far, we have supported many cosmetic factories in Europe, Asia and America to develop new products.
Partner with Baisifu today, for high quality quaternium 73 for your cosmetic products – Get free samples now.

No, it does not prevent microbial growth but mainly used for conditioning, moisturizing and softening hair or skin.
Quaternium indirectly treats acne by reducing irritation from harsh cleansers or active acne treatments.
It does not treat acne directly the way salicylic acid or retinoid do rather it moisturizes and soothes skin to prevent friction-related breakouts.
Absolutely yes, it has regulatory approval by major authorities like EU cosmetics Regulation hence its safe and widely used in skincare and hair care.
Quaternium 73 is used in shampoos, conditioners and cleansers as a conditioning polymer because it moisturizes, and softens skin and hair.
Whereas quaternium 15 is used in creams, lotions and soap and as a preservative because it releases formaldehyde to prevent microbes that may cause allergies.
Yes, samples can be requested for testing or small scale formulation before bulk orders.
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