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Sodium Acetylated Hyaluronate

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Acetylated hyaluronic acid sodium salt (AcHA), derived from sodium hyaluronate (HA) through acetylation, combines both hydrophilic and lipophilic properties due to the introduction of acetyl groups. This makes AcHA highly compatible with the skin, providing dual-action hydration and aiding in the repair of the skin barrier, which helps improve dry and rough skin, leaving it soft and elastic.

If you are looking for a sodium acetylated hyaluronate supplier, Baisifu is your best option. We provide cosmetic-grade super hyaluronic acid with high purity.

CAS Number: 158254-23-0

Appearance: White Powder

INCI: SODIUM ACETYLATED HYALURONATE

CAS Number 2
Appearance : White Powder
Common Benefits for the Skin

Skin elasticity and excellent moisturizing effect. The acetyl group functions as an anchor, helping the HA molecules to stick to the skin surface more effectively. This means they stay longer on the skin while providing extended hydration and improved elasticity.

Skin barrier repair. Sodium acetylated hyaluronate stimulates skin proliferation. It can repair the damage cells within the skin epidermis. This helps in strengthening the stratum corneum barrier function. It also helps in reducing water evaporation to prevent skin roughness and dryness.

Improving signs of aging. Aside from skin plumping and hydration, AcHA protect skin from environmental damage. This results in reduced wrinkles and fine line appearance.

Sodium Acetylated Hyaluronate Uses

Baisifu offers sodium acetylated hyaluronate for sale that is widely used for different applications including:

Skin care. AcHA is ideal for skincare products such as body wash, cleansing soaps, creams, facial cleansers, serums, moisturizers, and more.

Cosmetics. You can use AcHA for formulation of UV protection, creams, toners, make-up, essence.

Technical Specifications
Molecular Formula (C14H20NNaO11)n
Solubility Water
pH 5-7
Purity 99%

Mechanism of Action

Mechanism of Action

Enhanced Penetration

The acetylation reaction decreases the molecular mass of sodium hyaluronate, which in turn increases penetration of cellular skin. Research shows that acetylated hyaluronate is more readily dissolved in the skin than its non-acetylated counterpart.

Better Moisture Retention

The hydrophility of hyaluronate is increased because acetylated hyaluronate has acetyl groups. This augmentation of structure improves the capacity to hold water molecules, which raises its capacity to hold moisture in the layers of skin. Consequently, your skin will be in a better position to maintain its level of hydration over extended periods of time.

Skin-feel and Elegance

The altered product of acetylated hyaluronate also helps to produce a light, non-greasy texture in cosmetics. This makes the application a lot easier and makes it feel good to you. It also becomes more stable, thereby reducing degradation of the product and reducing fluctuations in performance.

How Sodium Acetylated Hyaluronate Outperforms Other Forms

How Sodium Acetylated Hyaluronate Outperforms Other Forms

The different benefits of Sodium Acetylated Hyaluronate (SAH) over other derivatives of hyaluronic acid in cosmetic formulations are as follows. A technical comparison showing its superior features is given below.

Regular Hyaluronic Acid 

Hyaluronic acid is heavy in molar weight, and it cannot penetrate your skin. It mainly moisturizes the skin surface, which gives it a short time moisture. HA is not effective in providing more deeply-skinned benefits, due to its size.

Hydrolyzed HA

Hydrolyzed HA breaks down enzymatically to smaller molecules. This addition contributes to the fact that it enters the skin more easily than normal HA. But it might not have the long-term hydration and skin affinity equivalent to

Sodium Hyaluronate

Sodium Hyaluronate is the salt of HA and is more easily soluble and stable. It enters the skin more than HA but not so well as SAH. SH mainly moisturises the surface skin, and its effect lasts shorter than that of SAH.

Property Regular HA Hydrolyzed HA Sodium Hyaluronate Sodium Acetylated Hyaluronate
Molecular Size Large Small Medium Small
Skin Penetration Limited Moderate Good Excellent
Hydration Duration Short Moderate Moderate Long-lasting
Skin Affinity Low Moderate High Very High
Suitable for Sensitive Skin No Yes Yes Yes

Formulation Tips & Usage Recommendations

Formulation Tips & Usage Recommendations

Typical Concentrations

Add Sodium Acetylated Hyaluronate 0.01 -0.1%. This is the maximum achievable content of alcohol and provides the highest levels of hydration and skin affinity without disrupting the stability of any formulation. Research also shows that it increases the skin elasticity and moisture retention by 0.1 percent substantially.

Suitable Product Types

You will find it in serum, creams, gels, lotion, and eye masks. It can also be subjected to water-formulations and oil-formulations in addition to improving the performance of products in other cosmetic uses.

Skin Types

Applicable to all skin types, such as sensitive, dry, and dehydrated skin. It is also biocompatible, which means it can be used with very little irritation. Moreover, it is considered a very popular add-on ingredient for skin-care design.

Synergistic Pairings

Forms well with peptides, ceramides, niacinamide, and antioxidants. These compounds make it perform more moisturizing action, for the skin, as well as for more repairing and anti-aging purposes, and it is completely beneficial to the skin.

Application Tip

You can use it on wet skin to get the best level of hydration. Apply a moisturizer to seal the moisture and increase the effectiveness of the ingredient. The method can ensure the optimum absorption and long-term skin hydration.

Why Choose Baisifu as your Sodium Acetylated Hyaluronate Supplier

Why Choose Baisifu as your Sodium Acetylated Hyaluronate Supplier

Baisifu is a trusted sodium acetylated hyaluronate supplier with years of experience in manufacturing cosmetic ingredients. As a CGMP compliant manufacturer, we have adopted sustainable and safe production processes to produce high grade cosmetics ingredients. 

For every bulk order, Baisifu avails certificates of analysis (COA), technical data sheets (TDS), and material safety data sheets (MSDS). Furthermore, our team can also help you in cosmetic products formulation upon request.

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