18β-Glycyrrhetinic Acid

Description:

Glycyrrhetinic acid belongs to licorice extract, appearing as white to off white crystalline powder, insoluble in water and soluble in acetic acid, acidic and stable at room temperature.β-Glycyrrhetinic acid can be anti-inflammatory, antioxidant, antibacterial, regulate skin immunity and enhance barriers, and is friendly to sensitive muscles. β-Glycyrrhetinic acid commonly used in lotion, face cream and other products, it can relieve, anti-aging and acne.18β-Glycyrrhetinic Acid China Supplier,Baisifu, focuses on high-quality products, certified by ISO 9001&ISO 14001, adheres to animal free testing, comes with COA, MSDS, TDS reports, and provides free samples.

Cas No.:471-53-4

Appearance:White to off-white Crystalline Powder

Similar Name: β-Glycyrrhetinic acid

Solubility:Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.

Benefits:

18β-Glycyrrhetinic Acid has strong anti-inflammatory ability, which can effectively inhibit inflammation, reduce skin inflammation caused by UV radiation, chemical substances and other stimuli, and relieve redness, swelling and itching. Excellent anti allergic performance, can regulate skin immune response, reduce allergic sensitivity, and alleviate allergic symptoms. At the same time, it has significant antioxidant effects, can eliminate free radicals, delay skin aging, and maintain skin elasticity and radiance. In addition, β-Glycyrrhetinic acid can regulate skin oil secretion, improve oil-water balance, and make the skin healthier.

Package:

Baisifu currently has wholesale prices for 18β-glycyrrhetinic acid for sale.This product is packaged in powder and comes in two sizes, 1kg/bag and 25kg/box.

General Information:

Source & Extraction Process

The fresh licorice roots are grown in monitored areas where clean material is obtained to be processed. The roots are then subject to washing and drying which makes them ready to be extracted easily. Warm extraction producesglycyrrhizin, which is then hydrolyzed and then purified carefully to obtain stable 18 2 -Glycyrrhetinic Acid.

The gradual flow is beneficial in maintaining a stable quality due to tight control of impurities in each phase. Light separation preserves the active structure and enhances stability in skin-focused formulas in general. These controlled steps ensure that the ingredient remains strong, clean, and simple to work with.

Key applications in Cosmetic Industry

18β-Glycyrrhetinic Acid functions in calming, tone-balancing, and protective functions in spa and medically developed skin care formulations.

• Skin care lotion: The active ingredient calms skin surface irritation and increases comfort for the skin through calming action. It protects the skin and balances emulsion lightness in a gentle way.
• Face cream: The active ingredient calms the skin and improves skin comfort in a richer cream. It smoothens the texture and enhances the cream’s performance.
• Acne products: The active ingredients calms and reduces redness from active breakouts and so supports clearer skin. It protects the skin when applying concentrated, and thus active, products.
• Facial mask: The active ingredient calms mask-induced skin tension and improves comfort during mask wear. It enhances uniformity of the mask and protects emollient and moisture-rich formulations.
• Toner: The active ingredient evenly calms the skin surface and reduces visible irritation. It stabilizes the formula and helps the product maintain a clean, bright appearance.

Mechanism of Action

18β-Glycyrrhetinic Acid relieves redness and irritation by calming the stress response at the nervous system level. This calming effect regulates defensive local responses that dictate discomfort and dysregulation. The ingredient maintains a calm surface environment through smooth and constant action.

Itsstructure also has antioxidant properties that help mitigate the damage done from the stressors at the surface of the skin. This protective action relieves the stress at the surface and broadens the calming profile of the formulation. The combination of these actions creates a high level comfort where calming activity is very much needed.

Formulation Guidelines

· Solubility

The active ingredient is highly soluble in oils, glycols, and some alcohols but is poorly soluble in water. Pre-solubilizing in an appropriate solvent prevents production of an unevenly dispersed product. Thus, the process helps ensure the product’s consistency as well as stability during its entire shelf life.

· pH Stability Range

Most formulation types show stable activity at pH 4.5 to 7.5. This range of stability covers both very light toners and very dense emulsion systems. It also provides protection to the ingredient’s natural soothing power.

· Usage Percentage Range

Commonly, the usage rates are kept in the range of 0.1% to 0.5% depending on the formulation and effect desired. Higher amounts may be observed in specialized calming formulations. However, lower levels are suitable for soft and non-irritating daily use.

· Compatibility with Other Actives

The ingredient is compatible with niacinamide, ceramides, panthenol, hyaluronic acid, and even mild exfoliants. The presence of strong acids or highly reactive compounds at high concentrations might cause instability. Pre-testing helps to keep blends predictable and smooth.

Safety & Regulatory Compliance

Our quality system maintains control of Identity, purity and microbiological safety to ensure compliance worldwide. Each batch is accompanied by complete documentation system to facilitate and streamline your approval steps. Our documentation attests to consistent and responsible sourcing.

You have access to certificates of analyses, material safety data sheets, and technical documentation that are instrumental in regional submissions without backlogs. We also help your team to answer regulatory questions to facilitate product development cycles. Our system delivers reliable traceability from raw material to final ingredients.

Why Choose Baisifu as your Glycyrrhetinic Acid Supplier in China

Baisifu is your ISO 22716glycyrrhetinicacid supplier in China. Our cosmetic-grade glycyrrhetinicacid are formulated to conform to the industry safety standards.

With every order, you get a certificate of analysis, alongside product datasheet. Upon request, our Baisifu team can also help you get the right formulations for your new products – Get free samples now.

FAQs

1. What are the typical purity ranges for 18β-Glycyrrhetinic Acid?

The purity ranges are typically from 85% to 98%.

2. What is the best way to disperse the powder to minimize clumping during processing?

In order to minimize clustering of powder, pre-disperse it in oil or glycol prior to introduction to the batch.

3. What is the typical sensory experience for the skin after application?

The product typically has a very soft, gentle, and light sensory experience.

4. Is 18β-Glycyrrhetinic Acid heat-sensitive when being processed?

Yes. Excessive heating for prolong periods of time will compromise structural integrity.

5. Does 18β-Glycyrrhetinic Acid change the color or scent of the final cosmetic products?

No. This ingredient is color and fragrance neutral and does not affect either.

6. Is it appropriate for and “clean beauty” and fragrance-free products?

Yes, it is compatible with minimalist and fragrance-free products. It fits “clean beauty” philosophies.