Adenosine

Adenosine is a purine ribonucleoside formed by adenine attached to ribose, found in every cell of the human body. This important nucleoside has an essential function in several biochemical activities like  energy transfer, signaling pathways, and RNA synthesis. Phosphorylated adenosines are central to cellular energy management and have regulatory functions over various essential processes within the body.

If you are seeking premium-quality adenosine, we offer high-purity adenosine sourced from China. Produced using advanced fermentation technology, our adenosine is ideal for biopharma, cell culture media production, diagnostic applications, and cosmetics formulations.

CAS Number: 58-61-7
Appearance: White Powder

Uses in Research and Medicine

Adenosine in cosmetics serves as an antioxidant, skin conditioning agent, and moisturizer. Its main benefits and mechanisms of action are as follows:

Anti-Wrinkle Effects: Adenosine is a precursor to adenosine triphosphate (ATP), the energy carrier within cells. It provides essential energy to skin cells, maintaining normal cellular metabolism. Adenosine can prevent the oxidation of proteins by free radicals, thus preventing the loss of tissue elasticity and skin laxity, contributing to wrinkle prevention, skin smoothing, and pore tightening.

Skin Brightening Effects: At certain concentrations, adenosine can inhibit the activity of B16 melanocytes, aiding in skin brightening.

Anti-Inflammatory Effects: Adenosine works by binding to G protein-coupled receptors on cell membranes, regulating innate and adaptive immune responses. It modulates the differentiation and maturation of immune cells and the release of cytokines and chemokines, thereby suppressing inflammation and protecting surrounding healthy cells from damage.

Hair Growth and Hair Loss Prevention: Adenosine promotes blood circulation. It can stimulate hair growth and promote the production of FGF-7 factors and thicker hair strands. Additionally, it has direct effects on dermal papilla cells, which play a crucial role in new hair growth and maintaining existing hair.

Formulation Guidance

It dissolves well in water and, hence, can be used in serums or emulsions. The stability is best kept in the pH range of 4.5 to 6.0. Adding it in a controlled way ensures a steady performance.

They are generally used in levels of 0.1% up to 3%, depending on the application. Addition is preferred only during cool-down phases to conserve its delicate structure and functional efficacy.

It blends nicely with peptides, moisturizers, and antioxidants for a synergistic effect. Highly acidic actives can degrade it. Proper pairing keeps the formulations stable with consistent performances.

When it comes to various quantities in cosmetic products, you can consider:

• 5% to 2.0% for anti-wrinkle and antioxidant effects
• 1% to 0.6% for skin brightening effects
• 1% to 3% for hair loss prevention and promoting hair growth

Compatibility with Other Cosmetic Ingredients

First, adenosine is water-soluble. This makes it a perfect choice for water-based cosmetic products.

However, the problem come when you want to dissolve higher concentrations, which may prove difficult to dissolve.

The best part, adenosine has a broad working PH which varies between 3.5 and 6.5. Therefore, it is compatible with many cosmetic ingredients.

Among the key cosmetic ingredients you can mix with adenosineincludehyaluronic acid, vitamin C, retinol, niacinamide, and peptides. This allows you to make more effective products that target various skin conditions.

Safety Profile

Adenosine is generally safe for use in many cosmetic products formulations. They are safe in the recommended concentrations.

It is non-toxic and well-tolerated by the skin, with no serious allergic reactions. In most cases, the concentration may range from 0.1% to 1%.

Additionally, there is country that has prohibited the use of adenosine in cosmetic products formulations.

Why Choose Baisifu as your Adenosine Supplier in China

Baisifu is your trusted adenosine supplier in China. As an ISO 22716 adenosine manufacturer, we adhere to strict safety and testing protocols to ensure the products conforms to high quality standards.

With every adenosine bulk purchase, you get product data sheet and certificate of analysis (CoA).At every stage, Baisifu works with your factory to ensure you get high quality cosmetic-grade adenosine – request for free sample.

Technical Specifications