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Guaiazulene

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Guaiazulene is a multifunctional biologically active substance based on azulene. It is widely used in the pharmaceutical and cosmetic product formulation.

This active substance has a soothing property and sensitive to the change in pH and light.

If you are looking for a trusted guaiazulene supplier, Baisifu is your best choice. You can assure that we provide these substances with batch-to-batch consistency. We have guaiazulene for sale in China and around the globe according to the needs of customers.

CAS Number: 489-84-9

Appearance: Dark blue crystals or viscous liquid; upon exposure to light, it changes from dark blue to green, and finally to yellow.

CAS Number 2
Appearance : Dark blue crystals or viscous liquid; upon exposure to light, it changes from dark blue to green, and finally to yellow.

Guaiazulene CAS:489-84-9

Guaiazulene Benefits

This active substance has many essential features and benefits including:

  • Temperature sensitivity. It changes into an oily liquid, so when the temperatureis above 28°C, it can be easily dispersed in a product matrix.
  • FDA Approved. Our guaiazulene is an approved cosmetic color additive and used with other skin-soothing ingredients.
  • This ingredient is photosensitive and can form reactive oxygen species.
Technical Specifications
Item Specification
Appearance Dark Blue Liquid or crystal
Identification It shows absorbance of maximum at 604-608nm
Freezing Point ≥30℃
Water ≤0.1%
Residue on Ignition ≤0.1%
Purity (GC) ≥99.9%

 

Mechanism of Action

Mechanism of Action

Guaiazulene has a variety of positive activations in cosmetic and pharmacological preparations. The main mechanisms through which this ingredient acts to increase the efficacy of the product are as follows: 

Let our clients know how these ingredients work when they use them to formulate their products.

  • Anti-Inflammatory Pathways

Guaiazulene inhibits pro-inflammatory cytokines, which increase skin irritation. It works by both moderating the immune response to inflammation and soothing and replenishing the skin.

  • Antioxidant Action

Guaiazulene is an antioxidant that helps in preventing oxidative damage to the cells. This decreases aging and stress on the skin caused by the environment.

  • Membrane Stabilization

It interacts with the lipids of cell membranes to fortify them, making them resistant to external stress factors that may cause cell membrane damage. The move keeps the skin intact and increases its strength.

  • Antimicrobial Effects

Guaiazulene is an antimicrobial with the ability to prevent bacterial growth. This keeps the skin healthy during formulations and reduces the chances of infections.

  • Broad Biomedical Potential

It has a wide application in the field of biomedical practice and enhances skin barrier functions. It can be used in many different formulations that address different skin issues because of its versatility.

Applications & Uses

Applications & Uses

  • Cosmetics & Colorant

Guaiazulene is a natural colorant that is used in cosmetics. It gives a bluish color to the products and has soothing and anti-inflammatory properties on the skin.

  • Pharmaceutical & Therapeutic Uses

Guaiazulene is used as a medicinal agent in the preparation of pharmaceutical compositions, especially in the treatment of ulcers. It is used for the treatment of gastrointestinal diseases because it helps reduce inflammation and heal tissue.

  • Used as Anti‑Ulcer Agents

By decreasing irritation and mucous membrane regeneration, guaiacene is used in the treatment of ulcers. It promotes the treatment methodology of curing ulcers and other intestinal complications.

  • Asian and Western Formulations

Guaiazulene is a common ingredient in Asian and Western skincare products. It is a type of anti-inflammatory and antioxidant component that makes it suitable for sensitive skin products.

Other Cosmetic Ingredients that Work with Guaiazulene

Other Cosmetic Ingredients that Work with Guaiazulene

In designing products that contain Guaiazulene, people tend to add other ingredients to exploit its full potential. These compounds together increase the calming, anti-inflammatory, and repair properties of Guaiazulene, and also increase skin hydration, irritation, and general skin health. Some of the most prominent ingredients that are usually combined with Guaiazulene in cosmetic preparations are listed below:

  • Hyaluronic Acid
  • Niacinamide
  • Vitamin C
  • Peptides
  • Ceramides
  • Aloe Vera Extract
  • Tea Tree Oil
  • Witch Hazel Extract
  • Alpha Arbutin

Safety, Regulations & Precautions

Safety, Regulations & Precautions

Guaiazulene is considered overall safe when used either in cosmetics or pharmaceuticals. Meets the regulations for use in different markets around the world (e.g., Europe and North America).

Regulatory Status

  • FDA

Guaiazulene is not an ingredient that is restricted by the FDA at present. According to the FDA, it is safe to use in cosmetic formulations as it is not toxic.

  • Health Canada

Guaiazulene is safe, and it was approved by Health Canada to be used in cosmetics with reduced safety limits. It complies with the specifications of cosmetic ingredients by the Cosmetic Ingredients Hotlist.

  • EWG Ratings

Guaiazulene is low risk on the Environmental Working Group (EWG) database. It is believed to be non-toxic to most types of skin when applied in allowed concentrations.

Safety Data & Handling Advice

  • Sourced from SDS

 As the Safety Data Sheet (SDS) indicates, Guaiazulene is to be treated under the typical laboratory work precautions. You should not touch your eyes or spend a long time in contact with your skin. Store it in a cool, dry place.

  • Environmental Precautions

Guaiazulene has to be discarded as per local policies. In order to restrict the ecological footprint, it is not suggested to release it into the environment.

Why Choose Baisifu as your Guaiazulene Supplier

Why Choose Baisifu as your Guaiazulene Supplier

Baisifu provides high-quality (Guaiazulene) that is acquired in the most sustainable and quality-focused manner. Our ingredient is rigorously tested for consistency, purity, and potency. We offer reliable supply chains, technical support, and products specifically for your needs in formulations. Relax with the best ingredients and the best service at Trust Baisifu.

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