Caffeic Acid exhibits a broad spectrum of antimicrobial and antiviral effects, complemented by its capability to absorb ultraviolet light. Even at low levels, this compound is efficacious in curtailing the production of skin melanin. Possessing strong antioxidant qualities that span a wide range, Caffeic Acid can prevent the formation of lipid peroxides. Thus, it is highly recommended for its potential to provide antioxidant protection, reduce inflammation, promote skin lightening, and enhance skin condition in cosmetic products.
It belongs to a micronutrient called polyphenol, which is popular for its natural antioxidant properties. This compound helps boost athlete performance and is anti-inflammatory and antiviral.
Baisifu is a reliable caffeic acid supplier in China, offering this compound in bulk packaging sizes of 1kg, 5kg, 10kg,25kg
CAS Number: 331-39-5
Appearance: Yellow crystalline powder
Other Name: 3,4-Dihydroxycinnamic acid
| CAS Number | 331-39-5 |
| Appearance | Yellow crystalline powder |
Antioxidant. This compound is a natural antioxidant that prevents oxidation in the body. It protects damaged cells that may cause cancer, heart disease, etc.
Health Benefits. It helps in preventing diabetes, inflammation, neurodegenerative disease, and fatigue.
Skin Benefits. It helps protect the skin from UV radiation, preventing premature aging while maintaining ang young-looking skin.
Due to its tremendous benefits, caffeic acid is widely used for supplements and cosmetic formulations.

| Chemical Formula | C9H8O4 |
| Molecular Weight | 180.16 |
| Assay | 99% |

Most antioxidants only have one way to neutralize but caffeic acid offers a broader spectrum of benefits. Its superior performance is due to its unique chemical structure, the catechol group. In particular, caffeic acid has an extraordinary ability to scavenge reactive oxygen species due to the ortho-dihydroxy configuration on the benzene ring.
It is consistently better than single-function antioxidants typically used in standard cosmetic formulations because it is such a good free radical scavenger.
Caffeic acid inhibits the enzyme directly responsible for melanin synthesis, tyrosinase, as well as the matrix metalloproteinases responsible for collagen breakdown. Adding this one ingredient, you can add to your brightening and anti-aging lines without adding complexity to your raw material inventory.

The global caffeic acid market is valued at USD 2.1 billion in 2022 and is projected to reach USD 3.83 billion by 2033 at a CAGR of 6.9 %. A lot of it is being driven by the forward-looking manufacturers who are already making natural antioxidant skincare lines around high-performance cosmeceutical ingredients.
Consumer demand is moving so fast to plant-based active ingredients and the inclusion of caffeic acid is an easy way to have your formulations ahead of the trend.
The market reality is that clean beauty formulation is shifting and your R&D team should not ignore that. Retailers, distributors and end buyers are actively seeking natural phenolic acid actives backed by credible efficacy data. Caffeic acid meets both needs perfectly. It is a polyphenol antioxidant with proven performance and a clean sourcing story that meets the requirements of clean label cosmetics.

Let’s compare caffeic acid to the more common alternatives your team is likely already evaluating.
Both are derivatives of hydroxycinnamic acid and have shown to provide UV photoprotection and free radical scavenging activity in a reliable manner.
Which One to Choose?
Resveratrol and Vitamin C are industry standards, but they both have their formulation issues that caffeic acid does not.
Moreover, its stable acidic pH window of 3.5 to 5.5 makes it much easier to formulate across both brightening and anti-aging serum formulation categories.
| Caffeic Acid | Ferulic Acid | Resveratrol | Vitamin C | |
| Free Radical Scavenging | Excellent | Excellent | Good | Good |
| Tyrosinase Inhibition | Strong | Moderate | Moderate | Moderate |
| MMP Inhibition | Yes | Limited | Limited | No |
| Formulation Stability | Moderate | High | Low | Low |
| Cost Efficiency | High | High | Low | Moderate |
| Best Fit | Brightening + Anti-aging | SPF + Vitamin C blends | Antioxidant defense | Brightening |

Caffeic acid delivers measurable results in multiple high-demand product categories. This is where it can add most value in development.
Caffeic acid is a direct tyrosinase inhibitor mechanism for the formulation of a skin brightening serum or a targeted hyper-pigmentation treatment ingredient product. This functional specificity gives you the ability to command a premium position in the cosmeceutical ingredient space. We provide HPLC purity 99% caffeic acid with complete batch documentation to help support your brand story.
It’s a wonderful base for any anti-pollution cream or urban defense line, as caffeic acid neutralizes the reactive oxygen species that are so efficiently triggered by urban pollutants. It also helps to enhance the protection of the epidermal barrier, providing a strong dual-function claim for your finished formula.
The addition of caffeic acid to a sun care system combats the oxidative stress left in the wake of traditional UV filters and directly prevents photoaging. This gives a complete protection story for the end consumer for sun care manufacturers. And with our dependable supply chain, you can increase your production without worrying about delays.

Most hair care formulators put all of their active ingredients on the hair strand and often ignore the scalp where most of the biochemical activity happens.
All of these – pollution, UV exposure and harsh chemical treatments – cause the build-up of reactive oxygen species on the scalp. This ongoing oxidative stress damages the delicate follicular environment and may disrupt the hair growth cycle. Brands working on scalp treatments or hair loss prevention products should consider the high free radical scavenging ability of caffeic acid, which speaks directly to this root-level damage.
Color protection is a major purchase driver, but most formulations only provide surface protection. Caffeic acid actively neutralizes the damage caused by oxidative hair dye systems deep at the level of the cortex.
Our GMP certified caffeic acid provides your product a defensible performance claim that stands out in a crowded marketplace.

The efficacy of caffeic acid is greatly enhanced in combination with complementary actives. Here are three powerful combinations to build around.
Vitamin C and caffeic acid combine to form a self-reinforcing antioxidant system. The natural acidic pH range of caffeic acid corresponds to the narrow stability window of Vitamin C, aiding to maintain the integrity of both actives in one formula.
This combination provides overall better free radical scavenging performance. This combination is a great choice for an antioxidant serum ingredient that targets uneven tone and premature skin aging .
Caffeic acid paired with niacinamide creates a potent, two-pathway brightening mechanism. Caffeic acid inhibits melanin synthesis on the enzymatic level by inhibiting tyrosinase and niacinamide prevents melanosome transfer into the skin cells.
This multi-step approach delivers visibly superior brightening results and reinforces the clinical credibility of your hyperpigmentation treatment product.
Peptides actively signal new collagen production and caffeic acid protects existing collagen from degradation by MMP inhibitors. Together, used in a night cream formulation or in an anti-aging serum formulation, they are attacking both sides of the anti-aging equation: production and preservation.
If you’re developing high-end anti-aging lines, this pairing provides a technical story that will easily pass professional review.

Baisifu provides premium, cosmetic grade caffeic acid in bulk to skincare, cosmetics and hair care manufacturers worldwide. Your production and compliance teams require extensive documentation and technical support for our product.
All batches are manufactured in strict ISO certified and GMP certified conditions with full traceability that your QC team can easily verify. You will receive a standard Certificate of Analysis, Safety Data Sheet and Technical Data Sheet with each shipment.
We have a low minimum order quantity of 1 kg so you can validate performance with production grade material before scaling to larger volumes. We also provide free samples on request for you to test our quality yourself.
We provide direct manufacturer pricing on all bulk orders of caffeic acid and have standard lead times of just 1 to 3 business days.
Contact our team at Baisifu today to request a custom quote.
No, they are completely different chemical compounds. The hydroxycinnamic acids include the stimulant alkaloid caffeine and the phenolic compound caffeic acid (CAS 331-39-5). For cosmetic manufacturers, the value of caffeic acid lies in its strong polyphenol antioxidant activity, not any stimulant properties.
The cosmetic grade caffeic acid with HPLC purity 99% is required as specification for skincare and personal care products. This level of high purity ensures consistent performance batch to batch and meets the rigorous standards for quality documentation demanded by today’s retail and private label buyers of their suppliers.
Yes, caffeic acid is an active ingredient of plant origin, a phenolic acid that occurs in nature. Its natural origin makes it compatible with clean label cosmetics and standards of natural formulation.
The effective utilization rate is 0.1%-1.5% for anti-aging serum formulation and skin brightening serum application. Reliable results can be obtained with a concentration of 0.05% to 0.5% in daily creams and moisturizers. As always we recommend running small-batch stability trials to confirm compatibility with your specific base formula.
Caffeic acid inhibits melanin production by directly binding to the active site of the tyrosinase enzyme, effectively interrupting the MITF signaling pathway that triggers pigmentation. If you are developing a product based on a hyperpigmentation treatment ingredient, this mechanism provides a simple, science-based brightening claim with proven efficacy.
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