Paeoniflorin is extracted from the root of the peony plant. It can also be isolated from the freshwater fern Salvinia molesta. Paeoniflorin extract can enhance cognition and alleviate learning disabilities. It has antioxidant, anti-inflammatory, anti-thrombotic effects, and has sedative, analgesic, and hypnotic effects. A 2019 study showed that Paeoniflorin supplement can also increase probiotics in the intestines and balance the intestinal microbiome. As a Paeoniflorin China Manufacturer and Supplier, Baisifu specializes in providing Paeoniflorin Powder for sale, equipped with COA, MSDS, TDS and other inspection reports, free samples can be provided, the company has passed ISO 9001 & ISO 14001 certification, and the products are non-animal tested.

Cas No.: 23180-57-6

Appearance: White powder

Solubility: Insoluble in water

Similar Name: Paeonia lactiflora P.E.

Paeoniflorin benefits:

Paeoniflorin has multiple biological activities, including significant anti-inflammatory effects, which can treat chronic inflammation and enhance human immune function. It also has antioxidant, analgesic, and intestinal microbial flora balancing effects.

Paeoniflorin uses:

Paeoniflorin has a wide range of uses, mainly in food, health products and cosmetics.

Package:

Our minimum order quantity is flexible and supports Paeoniflorin Wholesale, The packaging is 1kg/bag; 25kg/Carton.

General Information:

Paeoniflorin: Certified Extract for Pharma & Nutraceuticals

What Makes Paeoniflorin Worth Sourcing?

The natural anti-inflammatory market is moving fast and formulators sourcing generic botanical ingredients are already falling behind. Paeoniflorin extract is a multi-mechanism active which is effective for multiple uses. It has proven efficacy in pharmaceutical, nutraceutical and cosmetic applications.

This cross-category versatility is a direct reduction in your ingredient overhead. One single standardized botanical extract can be used for an anti-inflammatory capsule, a cognitive support formula and a topical skin calming serum, all within the same product portfolio.

What makes it commercially decisive is the science behind it. HPLC verified purity, clean sourcing from Paeonia lactiflora and consistent batch documentation means less troubleshooting for your QA team and more time to scale.

Where Does Paeoniflorin Come From?

· The Extraction Process

Paeoniflorin is extracted from the dried root of Paeonia lactiflora by ethanol extraction and purified by column chromatography. This process purifies the active monoterpene glycoside compound to precise, specification-grade levels.

· Why Botanical Source Matters for Purity

It is directly responsible for the bioactive consistency of your extract. This is where your QA validation process relies. Cultivated Paeonia lactiflora crops yield a much more predictable profile of alkaloids than wild-sourced material.

Paeoniflorin  is sourced from verified cultivation sites. You get a pharmaceutical grade botanical extract with full traceability from root to finished Paeoniflorin powder.

Technical Specifications

This is where every procurement team’s decision on bulk sourcing starts. These parameters define exactly what you are bringing into your facility and what your formulation can consistently provide.

Key Features of Paeoniflorin

Not all botanical extracts that claim high purity can prove it on a batch-to-batch basis.

· High Purity with Verified HPLC Standardization

Every batch of Paeoniflorin is quantified by HPLC test method that gives you a defensible purity number your regulatory team can submit with confidence. You get the data, not just the statement.

· Non-Animal Tested & Naturally Sourced

Paeoniflorin powder is made from Paeonia lactiflora root only and is not tested on animals. This supports your global positioning of clean label botanical extract.

· Stable Shelf Life & Consistent Batch Quality

With proper storage protocols, a two-year shelf life is backed up which makes your inventory planning predictable. Batch to batch consistency is built into our production process.

· Multi-Grade Availability

We offer pharmaceutical, nutraceutical and cosmetic grades from 10% standardized extracts to Paeoniflorin 98% pure. One supplier, every application your portfolio demands.

Benefits of Paeoniflorin

The wider the mechanism profile of your active ingredient, the stronger the market argument for your formulation.

· Powerful Anti-Inflammatory Action

Paeoniflorin extract targets several key inflammatory pathways such as NF-κB, TNF-α and COX-2, the same targets that fuel demand in prescription and OTC anti-inflammatory development. This makes it an active with scientific support, not just a botanical trend.

· Antioxidant Protection at the Cellular Level

It protects cellular integrity from oxidative stress by its free radical scavenging activity. For supplement and skin care brands, this means an anti-aging claim supported by data your marketing team can really stand behind.

· Neuroprotective & Cognitive Support

Paeoniflorin exhibits quantifiable neuroprotective activity in the research pipelines for both Alzheimer’s disease and Parkinson’s disease. This positions your product in a fast-growing therapeutic category for cognitive support botanical formulas.

· Analgesic Properties for Pain-Relief Formulas

Its natural analgesic and antispasmodic activity supports use for musculoskeletal discomfort and relief from dysmenorrhea. These are high demand OTC and nutraceutical categories with strong repeat purchase behavior.

· Gut Microbiome & Immune Modulation

Beneficial gut probiotics are promoted by paeoniflorin in clinical data. As a gut microbiome ingredient, it gives your immune health formulas a double-action positioning advantage.

· Cardiovascular & Liver Support

Its hepatoprotective and cardioprotective properties open up formulation possibilities in liver wellness and cardiovascular health, two of the fastest growing areas in functional nutrition.

Industry-Specific Uses of Paeoniflorin

The right active ingredient doesn’t just work in one formula, it opens up more revenue streams across your entire product portfolio.

· Pharmaceutical Manufacturers

Paeoniflorin is used in pharmaceuticals due to its proven activity against chronic inflammatory conditions such as rheumatoid arthritis and autoimmune pathways. It is a credible API intermediate botanical for OTC and prescription adjacent development pipelines, well documented with NF-κB and TNF-α suppression. Formulators in neurology are also adding it as a neuroprotective natural ingredient in Alzheimer’s disease and Parkinson’s disease research compounds.

· Nutraceutical & Dietary Supplement Brands

Paeoniflorin provides true multi-system support in one standardized input for nutraceutical raw material sourcing. At the same time it anchors formulas for cognitive support, joint health, immune modulation and gut wellness. That multi-benefit profile reduces your SKU complexity while supporting each product’s label claim story to retail buyers and practitioners.

· Cosmetic & Skincare Formulators

Paeoniflorin is seriously gaining traction as a topical anti-inflammatory ingredient in prestige and clinical skincare. Its ability to quiet IL-6-driven skin inflammation makes it directly applicable for rosacea soothing, anti-acne and skin brightening serums. It’s also botanical, non-animal tested and meets the clean beauty compliance mandates your retail partners are increasingly demanding.

· Herbal Extract Distributors

If you are developing a private label herbal extract catalog or supplying OEM nutraceutical manufacturing clients, consistent Paeoniflorin supply is a competitive asset. Distributors with high-purity Paeoniflorin with full documentation, COA, MSDS and TDS, can serve pharmaceutical and cosmetic buyers at the same time. We can offer this wide range of client service because of our flexible MOQ and stable supply chain.

Regulatory & Quality Compliance — What You Should Verify

The certification stack of your supplier is not a formality, it is the foundation of your market access.

· Certifications to Look For

At the very least, your supplier of Paeoniflorin should be ISO 9001 certified for quality management and ISO 14001 certified for environmental manufacturing standards for their extracts. Herbal extract manufacturing needs to be GMP certified to supply through the pharmaceutical channel.

If the Middle East or specialty retail are among your markets, Halal certified herbal ingredient and Kosher certified botanical extract credentials will rapidly expand your distribution reach.

· Documentation Standards

There should be a current Certificate of Analysis, MSDS and TDS specific to that production batch with every bulk shipment, not a generic document. Your QA team needs the HPLC verified purity data on a batch by batch basis to confirm incoming material meets your internal specifications.

We supply all standard documentation per batch as a base, not as an upgrade. Before committing to bulk volume, ask for your compliance package.

How to Choose the Right Paeoniflorin Grade for Your Product

Grade selection is where your sourcing decisions are building your formulation or subtly degrading it. Do this correctly first.

· Matching Purity to Application

The specification range of Paeoniflorin 10%-98% is based on the different needs of the active concentration of different applications. Cosmetic and functional food applications are generally in the lower standardized range while development of pharmaceutical grade botanical extracts and clinical nutraceuticals require Paeoniflorin 98% purity for accurate dosing integrity.

You cannot skip the step of matching your purity grade to your therapeutic or cosmetic claim, as it directly determines the credibility of the efficacy of your product to buyers and regulators.

· What to Ask Your Supplier Before Placing a Bulk Order

Request results for HPLC test methods, batch-specific, not averages for categories. If your formulation is inbetween standard grades, check to see if the supplier has options for custom purity herbal extract. Request information on the stability of the herbal ingredients and the lead times for your pack size.

Our technical team can match the right grade to your application spec before you buy volume.

Why Purchase a Bulk Order from Baisifu

Baisifu provides Paeoniflorin in high purity, directly from an ISO 9001 and ISO 14001 certified manufacturing facility, giving your procurement team a fully traceable, audit-ready source. Batch specific COA, MSDS and TDS documentation accompanies each bulk shipment which your QA team can cross check against your internal acceptance criteria all without chasing paperwork.

Our low MOQ herbal extract policy starts at 1 kg, so your formulation team can validate the performance of pharmaceutical grade botanical extracts before committing to larger volumes. You are able to request free samples of herbal extract to assess actual production grade material first.

Standard Paeoniflorin lead time is 1-3 business days on most orders. Contact us today for a custom quote for bulk Paeoniflorin supply.

FAQs

How should bulk Paeoniflorin extract be stored to maintain shelf life?

Store in a cool, dry place away from direct light at room temperature. Your Paeoniflorin powder will stay at full strength for two years if stored properly. This protects your investment in inventory.

How is the purity of Paeoniflorin extract verified during manufacturing?

Each production batch is tested for purity using HPLC. This provides your QA team with an exact, defensible active concentration number, not a range estimate.

What is the difference between Paeoniflorin and Total Glucosides of Peony (TGP)?

Total glucosides of peony (TGP) is a broader extract fraction that contains multiple glycosides including albiflorin and oxypaeoniflorin. Paeoniflorin is the only isolated primary active and it affords more accurate standardization for pharmaceutical formulations.

Is Paeoniflorin powder soluble in water for supplement and skincare formulations?

Paeoniflorin is soluble in ethanol, but not in water. Design your delivery system accordingly, as ethanol-based or lipid carrier systems work best for both oral capsule and topical anti-inflammatory ingredient applications.