Description:

Matrine is chemically stable and soluble in water. Matrine can fight inflammation, acne, oxidation and aging, regulate oil secretion, and optimize the water-oil balance of the skin. Normal dosage is safe, and excessive dosage may be irritating. Matrine powder is used in acne removal, anti-aging and oil control products, suitable for different skin types.Matrine China supplier, Baisifu, strictly focuses on quality, adheres to the concept of no animal testing, and provides COA, MSDS, TDS reports with transparent information and free samples for each product.

Cas No.:519-02-8

Appearance:White solid

Similar Name: alpha-matrine

Solubility:Soluble in Water (up to 25 mg/ml)

Benefits:

Matrine has anti-inflammatory effects, inhibits Propionibacterium acnes, relieves acne redness, swelling and pain, and prevents deterioration; matrine has antioxidant properties, scavenges free radicals, reduces cell damage, and delays skin aging; matrine can also regulate sebaceous gland secretion, reduce oil accumulation, maintain water and oil balance, keep the skin fresh, stable, and healthy, and effectively improve various skin problems.

Application:

Matrine is widely used in matrine supplements, acne products, anti-aging cosmetics, and oil control products

Package：

Baisifu currently has wholesale prices for matrine for sale.This product is packaged in powder and comes in two sizes, 1kg/bag and 25kg/box.

General Information:

Matrine: Natural Active for Hair & Skin Care Products

Where Matrine Comes From and Why It Matters for Sourcing

You get the wrong grade of matrine and you’ve ruined your formula before it’s even been tested. Here is everything you need to know.

· From Sophora Flavescens Root to Cosmetic-Grade Powder

The processors isolate matrine directly from the root extract of Sophora flavescens and purify it into a stable quinolizidine alkaloid with the molecular formula C15H24N2O. Its chemical identity is fixed under CAS 519-02-8 and EINECS 610-750-6 so every batch matches your COA. This rigidity means your production team will receive extremely predictable results from every run and every batch.

· Choosing the Right Purity Grade for Your Formula

Most manufacturers are actively specifying matrine 98% and validating it with stringent matrine HPLC purity testing to establish their cosmetic grade matrine baseline. This particular grade is consistent across a working pH range of 5.0 to 6.5, making it suitable for most leave-on and rinse-off bases. Upgrading to Pharmaceutical grade matrine is just additional cost with no additional skincare performance.

Choosing the right grade right away fixes your profit margins and keeps your formulation schedule right on track. The basics every formulator should ask for: a verified COA, confirmed purity grade, and full stability data.

The Science Behind Matrine’s Multi-Tasking Benefits

Using a single active ingredient to address three separate formulation challenges significantly simplifies SKU complexity and reduces development costs. And here’s what this ingredient does.

· Calming Inflammation & Acne-Causing Bacteria

With powerful matrine anti-inflammatory skincare benefits, it aggressively targets the bacterial activity associated with breakouts to function as a potent anti-acne ingredient for blemish-prone formulas. The active is still effective at pH 4.5 to 5.5, and it doesn’t irritate compromised skin barriers. This dynamic gives you a plant-based anti-acne ingredient that beautifully calms redness while consumers are actively demanding natural formulations.

· Antioxidant Power Against Skin Aging

Matrine antioxidant skincare ingredient properties are powerful in neutralizing free radicals that accelerate visible signs of aging such as fine lines and surface dullness. If you frame the material as a matrine anti-aging cosmetic ingredient, you can easily formulate potent serums and creams that stand toe to toe with high-end antioxidant blends. Your customers see results and you have a competitive claim based on real chemistry.

· Balancing Oil & Sebum Production

The powerful matrine oil control ingredient function regulates sebum output to effectively tackle one of the most highly requested benefits in shampoo and skincare briefs. This mechanism performs flawlessly in formulas kept near pH 5.5 to imitate the skin’s natural acid mantle for maximum efficacy. One simple ingredient covers three different claims and cuts down on the number of SKUs you have to manage on your production line.

Hair Care Applications Manufacturers Are Overlooking

Hair care formulators are always searching for synthetic actives, completely overlooking a multi-functional botanical that has already been proven in modern skin care. This is what you are not getting now.

· Scalp-Friendly Anti-Dandruff Formulas

Matrine anti-dandruff ingredient properties of reliable come directly from matrine unique activity on the specific yeasts and bacteria that cause flaking and scalp irritation. This unique matrine antifungal hair care attribute is a clean-label alternative to zinc pyrithione without sacrificing key efficacy claims. The ingredient shines at a shampoo pH of 4.5 to 5.5, matching the exact scalp-friendly formulations consumers expect today.

· Oil-Control Shampoos for Greasy Scalps

Targeted matrine for oily scalp applications address the root cause of greasy roots, regulating excess sebum right at the follicle level. This positioning instantly positions your shampoo as a premium targeted product, not a basic generic cleaner. Easily combines with mild surfactants at pH 5.0 to 6.0 for a beautifully balanced oil control rinse-off formula.

· Soothing Products for Sensitive, Itchy Scalps

Matrine in scalp care formulas for sensitive skin has a strong calming effect on itching and redness and actively supports the delicate protective barrier. It is one of the most versatile natural ingredients in shampoo formulation, because it allows you to market total gentleness without compromising on any performance data. These three specific applications make the material one of the most versatile botanical actives for hair care products on the market today.

· Skin Care Formulas Where Matrine Performs Best

Formulators creating targeted skincare lines need powerful actives that work in multiple product categories without endless reformulating. This ingredient is the best fit here.

· Acne & Blemish Treatments

Matrine for acne formulas, as a deep-acting anti-acne ingredient that is highly reliable for rapid spot treatments, is dedicated to acne. The active is highly stable at pH 4.5 to 5.5, yet keeps the final formulation surprisingly gentle on inflamed breakouts. This perfect balance gives you a power matrine anti-inflammatory skincare claim that acts on the bacterial cause as well as the resulting irritation.

· Oil-Control & Pore-Refining Products

The potent matrine oil-control ingredient severely regulates sebum at the source to tighten the look of enlarged pores. The base is prepared at pH 5.5 for stability of this activity and to match perfectly the natural surface chemistry of the skin. You get a visible mattifying effect for your customers and a very consistent formula for you.

· Anti-Aging & Antioxidant Serums

Matrine has proven antioxidant properties in skincare to protect the skin from severe oxidative stress associated with premature aging. It is a great matrine anti-aging cosmetic ingredient and works well with vitamin C and peptide actives in lightweight serums. You address three different categories with one single active and you make a much stronger case for choosing natural actives in cosmetics versus basic synthetics.

Recommended Usage Rates & Formulation Tips

Incorrect dosage and pH wastes expensive raw materials and destroys stability testing time. This is what works in practice.

· How Much Matrine to Add (Dosage Ranges)

Your target usage rate for matrine should be somewhere between 0.1% and 1.0%, depending on the application and your specific marketing claim. In the case of acne and oil-control products, a recommended dosage of 0.3% to 0.5% matrine generally produces highly visible results. At the lower end of the scale, antioxidant and soothing formulas work great to help you effectively control overall raw material costs.

· pH, Solubility & Stability Notes

The high water solubility of matrine makes it easy to introduce directly into the aqueous phase during standard processing. Matrine has a broad stability pH range of 4.0 to 7.0 so it covers most skincare and hair care bases without any sudden issues. Add powder only during the cool-down period to prevent the core activity from being exposed to heat for too long.

· Pairing Matrine with Other Actives

Top matrine compatible ingredients include niacinamide, panthenol and mild surfactant systems often used in daily cleansers and shampoos. Do not combine it with any strong oxidizing agents, since these will actively diminish its potency during your shelf-life testing period. Always do a quick small batch test first to ensure full compatibility before scaling up your matrine cosmetic formulation to full production.

Safety Data & Regulatory Status Buyers Should Check

Documentation gaps cause delays and frustration with customs compliance and slow down approvals with major retailers. Here is what you need to check before you place an order.

· Comedogenic Rating & Sensitivity Profile

The material has a very low matrine comedogenic rating making it ideal for formulations for acne-prone/oily skin without clogging pores. Its clean matrine safety data provides strong support for the formulation of dedicated matrine for sensitive skin products at standard cosmetic-use concentrations with no added risk. Before approval of a new supplier for large production runs, you MUST request the official matrine MSDS, matrine COA and a comprehensive toxicology summary.

· Compliance Across Major Markets

The current matrine cosmetic ingredient regulation status is different depending on the specific region, so it is always recommended to check the registration under matrine IECIC China cosmetic ingredient list for Asian markets. Please share the latest matrine TDS for both EU and US markets and confirm that it meets your strict regional regulatory standards. Your big product launch stays on schedule and fully compliant by verifying this key documentation on the front end.

Matrine vs Common Synthetic Acne Actives

All major global markets are seeing rapid change in acne treatment formulations as a result of clean-label claims. Here’s how this active compares to your current synthetic choices.

· Matrine vs Salicylic Acid & Benzoyl Peroxide

When direct matrine was compared with salicylic acid the botanical was found to be very effective at the much milder pH of 4.5 to 5.5. Salicylic acid usually needs a much lower pH of 3.0-4.0, which significantly increases the risk of irritation for sensitive consumers. It also positions your brand with a smart natural alternative to benzoyl peroxide for buyers looking for much milder, non-bleaching and plant-based actives.

· Cost, Sustainability & Clean-Label Value

The battle between Natural anti-acne actives vs synthetic options is guiding global purchasing decisions with major retailers pushing plant-based anti-acne ingredients on their shelves. Incredibly, the usage rate is 0.3% to 0.5% keeping your final cost per formula extremely competitive with harsh synthetic acid systems. When you use natural actives in your cosmetics, your entire product line becomes much more sustainable and that is what modern buyers want to hear about.

Why Purchase a Bulk Order from Baisifu

Baisifu is the direct manufacturer of matrine bulk ingredients China brands depend on. We provide complete documentation and technical support to meet your production schedule. For your compliance team, each shipment of cosmetic grade matrine comes with a ready to use COA, MSDS and TDS. Cutting out middlemen, sourcing from our matrine factory straight, to ensure a stronger matrine wholesale price.

We provide matrine bulk powder strictly tested at 98% matrine HPLC. Our matrine supplier team has you covered, fast, direct pricing from R&D samples to full shipping containers. Submit your request now and allow the experts to handle your precise requirements.

FAQs

What is matrine used for in cosmetic products?

It is used by formulators as a reliable anti-acne ingredient, a powerful antioxidant and a smart oil regulator for modern skin and scalp products. One active dynamic supports multiple claims with a huge reduction in SKU count and development costs.

What’s the difference between matrine and oxymatrine?

They are both quinolizidine alkaloid compounds directly extracted from Sophora flavescens, but oxymatrine is the oxidized form with quite different solubility metrics. Standard matrine has simply much better cosmetic compatibility for standard skincare formulations.

Can matrine help with dandruff or an oily scalp?

Yes, the active ingredient matrine has properties to fight the specific microbes that cause flaking. The dedicated matrine for oily scalp function successfully controls extra sebum to give you 2 powerful scalp-care claims from one single active.

What concentration of matrine is typically used in skincare formulas?

Most formulators settle on a working matrine use rate somewhere comfortably between 0.1% and 1.0%. The optimal concentration of Matrine for acne-specific and oil-control formulations is 0.3%-0.5%. This particular range keeps overall performance very consistent without unnecessarily raising material costs.

Can I buy matrine in cosmetic-grade purity for bulk manufacturing?

Yes, high quality cosmetic grade matrine with 98% matrine HPLC purity is still easily available in bulk powder form for large manufacturing-scale orders. Baisifu proudly supplies it with full verification documentation and a very competitive price for matrine wholesale.