Hexamidine diisethionate is an extremely effective antimicrobial ingredient. Being water-soluble, this cationic substance is active against bacteria, fungi, and yeasts. Thus, making it an ingredient for cosmetic and pharmaceutical applications.
It is also a polyvalent preservative that can be used as a cutaneous antiseptic. This helps in improving the skin health and hygiene. Whether you are looking for hexamidine diisethionate supplier for formulations, Baisifu is your best option. Our hexamidine diisethionate for sale is available in high purity grade and bulk quantity orders.
Hexamidine Diisethionate is an effective antimicrobial agent that provides broad-spectrum protection against bacteria, fungi, and yeasts. This water-soluble compound is widely used in the cosmetics industry as a preservative and skin disinfectant. Its multifunctional properties make it ideal for acne control, sebum regulation, reducing skin irritation, and preventing dandruff, thus enhancing the efficacy of both skincare and haircare products.
CAS Number: 659-40-5
Appearance: White Crystalline Powder
| CAS Number | 2 |
| Appearance | : White Crystalline Powder |


Hexamidine Diisethionate is used in acne treatment and prevention products, shampoos and hair care products, as a preservative, in deodorizing and antiperspirant formulas, and in emulsions, masks, gels, aqueous solutions, alcohol solutions, foam preparations, and sprays.
| Chemical Formula | C20H26N4O2C22H32N4O6S |
| Molecular Weight | 480.58 |
| Purity | 99% |
| Similar Name | Hexamidine 2-hydroxyethansulfonate |
Extraction of glycyrrhizic acid from licorice root happens first. Licorice root is powdered and solvent extraction is performed on it. We then filter this and concentrate it to give a glycyrrhizic acid-concentrated solution.
Purification follows, to obtain a highly pure product. Sugars and flavonoids are eliminated using precipitation and recrystallization. Ion-exchange chromatography allows selective separation and gives additional purity for refinement.
This then leads to neutralization of glycyrrhizic acid that has been purified. Treating with potassium hydroxide produces Dipotassium Glycyrrhizinate salt. Filtration and drying give a perfectly pure crystalline powder ready for formulations.
Maximum control is imposed over pH, temperature, and solvent ratio throughout production. This ensures stability and quality for every batch produced, resulting in a truly reliable ingredient for cosmetic manufacture.


Being highly water-soluble is one of the key features of Dipotassium Glycyrrhizinate. That makes it easy to incorporate into water-based formulations. You can formulate it into toners, gels, serums, and creams.
It is also soluble in glycols such as glycerin and propylene glycol. Such solvents are typical humectants in cosmetic product development. This renders the DPG compatible and versatile with various systems of formulation.
DPG is, however, not soluble in oils. This distinguishes it from oil-soluble licorice derivatives. Hence you are clear in choosing the kind of licorice extract to fit your product base.
DPG has an excellent safety record supported by regulatory approvals across the world. It is of low toxicity and low skin penetration. This renders it highly dependable for formulation in your cosmetics.
Third-party safety assessments ensure that it is non-irritant and non-sensitizing at levels of use. It is compatible with sensitive skin-oriented formulas. You have world compliance with no compromise on performance and safety.
Our quality measures also adhere to minimum purity levels of 98%. Product integrity is also supported by ISO certification and batches that are free of contaminants. This allows you to trust in the quality and compliance of the ingredients for your formulations.

Dipotassium Glycyrrhizinate blends well with brightening agents such as Vitamin C and Alpha-Arbutin to achieve stronger pigmentation control. Such combinations help you formulate more effective tone-correcting formulations.
It also gets along well with niacinamide, hyaluronic acid, and exfoliating acids. Such blends minimize irritation and improve hydration. Your products become milder, better balanced, and more acceptable for sensitive skin.
DPG is also compatible with retinoids and soothing botanicals like Centella Asiatica. It helps minimize dryness and irritation. This helps in alleviating the challenges in the development of innovative anti-aging products.
We produce Dipotassium Glycyrrhizinate to highest pharmacopeia levels, e.g., USP and EP. With our highly effective purification process, we guarantee a purity of more than 98%. Hence, you receive the same quality, customizable according to the requirements of the global market.
We offer technical support with our products, which ensures that they meet your particular formulation needs. Our experts are available to offer advice on how to maximize the benefits of the ingredients. This further ensures optimum performance value of the final product.
Every batch has to pass quality control and meet all legal regulations and requirements. For quality assurance, we are in possession of ISO certifications. We provide dependability, openness, and certainty in procurement.
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